| Product Name | MHC class II antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [3D6] to MHC class IIMHC Class II antigen is involved in the antigen presentation by APCs for CD4+ T cells. It is constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and is inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma. |
| Immunogen | Full length native protein (purified) (Rat). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3D6 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHC-FIPWB |
| Enumeration of B cells and monocytes. Localization of B cells/monocytes in tissue sections. Affinity purification of RT-1B antigen of different haplotypes. Characterization of leukemia and lymphomas. Pure RT-1B products are composed of two chains (alfa and beta) which under reduced SDS-PAGE have approximate MW. 32 KDa and 29 KDa, correspondingly: |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | INVG34 |
|---|---|
| Target | MHC class II |
| Tissue Specificity | Reacts with monomorphic determinant on beta chain of RT-1B molecules. Does not cross-react with RT-1A,-C,-D rat MHC products. |
| Cellular Localization | Cell Membrane |
| Light Chain Type | kappa |
| Application Notes | Enumeration of B cells and monocytes. Localization of B cells/monocytes in tissue sections. Affinity purification of RT-1B antigen of different haplotypes. Characterization of leukemia and lymphomas. Pure RT-1B products are composed of two chains (alfa and beta) which under reduced SDS-PAGE have approximate MW. 32 KDa and 29 KDa, correspondingly: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. We recommend to parafilm vials during storage to prevent evaporation of buffer. |
| Storage Buffer | PBS with 0.1% sodium azide, pH 7.4 |
