Application
Western blot analysis of MLK3 (pT277/S281) expression in HEK293T (A); NIH3T3 (B); PC12 (C) whole cell lysates.| Product Name | MLK3 (phospho Thr277/Ser281) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MLK3 (phospho Thr277/Ser281)The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MLK3 (pT277/S281). The exact sequence is proprietary. |
| Modification | p-Thr277/Ser281 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PTK1 SPRK MLK-3 mitogen-activated protein kinase kinase kinase 11 MLK3 MEKK11 MAP3K11 |
|---|---|
| Target | MLK3 (phospho Thr277/Ser281) |
| Tissue Specificity | Recognizes endogenous levels of MLK3 (pT277/S281) protein. |
Application
Western blot analysis of MLK3 (pT277/S281) expression in HEK293T (A); NIH3T3 (B); PC12 (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
