| Product Name | MMP14 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [9E10] to MMP14Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008] |
| Immunogen | human recombinant MMP-14 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 9E10 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Western blotting(1:400-800)|Immunohistochemistry(1:50-200): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MMP14 MT-MMP 1 MT1MMP matrix metallopeptidase 14 (membrane-inserted) MTMMP1 MT1-MMP MT-MMP 1 MMP-X1 |
|---|---|
| Target | MMP14 |
| Tissue Specificity | This antibody recognizes human MMP-14 in western blot without cross reactivity with human MMP-1-13, and MMP14-15. |
| Application Notes | Western blotting(1:400-800)|Immunohistochemistry(1:50-200): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
