Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary MMP17 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. HC = hepatocarcinomaApplication
Western blot analysis of anti-MMP17 Antibody (Center) in NCI-H460 cell line lysates (35ug/lane). MMP17(arrow) was detected using the purified Pab.| Product Name | MMP17 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MMP17The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases. Collectively, these enzymes can degrade all the components of the extracellular matrix, including fibrillar and non fibrillar collagens, fibronectin, laminin and basement membrane glycoproteins. In general, a signal peptide, a propeptide, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs. |
| Immunogen | Synthetic peptide - amino acids 434-448 of human MMP17 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For IHC-P: Use at a dilution of 1:50-1:100. For ELISA: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Matrix Metalloproteinase 17 Membrane-type 4 Matrix Metalloproteinase MT4-MMP 4326 602285 Matrix Metalloproteinase17 Membranetype4 Matrix Metalloproteinase MT4MMP4326 MT4MMP MT4-MMP Q9ULZ9 Matrix Metalloproteinase 17 Membranetype 4 Matrix Metalloprote |
|---|---|
| Target | MMP17 |
| Tissue Specificity | Not determined |
| Cellular Localization | Cytoplasmic/Cell membrane |
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary MMP17 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. HC = hepatocarcinoma
Application
Western blot analysis of anti-MMP17 Antibody (Center) in NCI-H460 cell line lysates (35ug/lane). MMP17(arrow) was detected using the purified Pab.| Positive Control | Human hepatocarcinoma tissue |
|---|---|
| Application Notes | For IHC-P: Use at a dilution of 1:50-1:100. For ELISA: Use at a dilution of 1:1,000. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. - Stable for six months after being received. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containig 0.09% sodium azide |
