Application
IHC-P analysis of human placenta tissue using MMP7 antibody at 1:50-1:200.| Product Name | MMP7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4C21] to MMP-7Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
| Immunogen | human recombinant MMP-7 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 4C21 |
| Host Species | Mouse |
| Tested Applications | IHCIHC-PWB |
| Western blotting(1:500-2000)|Immunohistochemistry(1:50-200): |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | matrix metallopeptidase 7 (matrilysin uterine) MMP7 PUMP-1 MPSL1 |
|---|---|
| Target | MMP-7 |
| Tissue Specificity | This antibody recognizes human MMP-7 in western blot without cross reactivity with other human MMPs. |
Application
IHC-P analysis of human placenta tissue using MMP7 antibody at 1:50-1:200.| Application Notes | Western blotting(1:500-2000)|Immunohistochemistry(1:50-200): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
