Application
Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE diluted at 1:500| Product Name | MMP8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MMP8 (matrix metallopeptidase 8 (neutrophil collagenase))Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MMP8. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CLG1 antibody HNC antibody MMP-8 antibody PMNL-CL antibody MMP8 antibody neutrophil collagenase antibody PMNL collagenase antibody matrix metalloproteinase-8 antibody matrix metalloproteinase 8 (neutrophil collagenase) antibody matrix metallopepti |
|---|---|
| Molecular Weight(MW) | 53 kDa (note) (4) |
Application
Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE diluted at 1:500| Positive Control | A549 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
