| Product Name | MOG antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [CE1] to MOGMyelin / Oligodendrocyte Specific Protein (MOSP) (pI of ~6.7) is found exclusively on oligodendrocytes and myelin in the central nervous system (CNS). Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. On demyelination, immunoreactivity for MOSP, like MBP, is lost. |
| Immunogen | Glial membrane proteins followed by rat CNS white matter. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | CE1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-F |
| Not tested in applications other than those listed above. Optimal dilutions / concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseMonkeyRatCat |
| Concentration | 0.2mg/ml |
| Target | MOSP |
|---|---|
| Cellular Localization | Cell membrane. |
| Positive Control | Brain. |
|---|---|
| Application Notes | Not tested in applications other than those listed above. Optimal dilutions / concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
