Mouse Monoclonal antibody [4G9-B4-B8] to MPIPhosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
Immunogen
Purified recombinant human MPI protein fragments expressed in E.coli.