Mouse monoclonal antibody [S2-16] to mSlo3Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+).
Immunogen
Fusion protein amino acids 1052-1121 of mouse Slo3; accession number AAB99742
Key Feature
Clonality
Monoclonal
Isotype
IgG2
Clone Number
S2-16
Host Species
Mouse
Tested Applications
ICC/IFWB
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).:
Species Reactivity
Mouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Target
mSlo3
Molecular Weight(MW)
115kDa (note)
Application
Application
Western blot analysis of Slo3 in rat brain membrane lysates using a 1:1000 dilution of
Application Notes
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.