Application
Human Breast Carcinoma stained with anti-MUC-1/EMA/Epithelial Membrane Antigen antibody| Product Name | MUC1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MUC1MUC-1 is a heavily O-glycosylated transmembrane protein expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC-1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. |
| Immunogen | The immunogen corresponding to a region within amino acid 1067 and 1255 of human MUC1 (Swiss-Prot entry P15941). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For ICC/IF: Use at a dilution of 1:500: |
|
| Species Reactivity | HumanMouse |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | mucin PEMT MUC1 PUM 4582 158340 P15941 EMA PEM H23AG MAM6 CD227 |
|---|---|
| Target | MUC1 |
| Cellular Localization | Cell Membrane and Cytoplasmic |
Application
Human Breast Carcinoma stained with anti-MUC-1/EMA/Epithelial Membrane Antigen antibody| Positive Control | MCF-7 cells and Breast carcinoma |
|---|---|
| Application Notes | For ICC/IF: Use at a dilution of 1:500: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide |
