Application
Human Stomach stained with anti-Mucin 5AC antibodyApplication
Human Stomach Adenocarcinoma stained with anti-Mucin 5AC antibodyApplication
Human Colon Adenocarcinoma stained with anti-Mucin 5AC antibody| Product Name | Mucin 5AC antibody (ready-to-use) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [SPM297] to Mucin 5ACMucins are high molecular eight glycoproteins with 80% carbohydrate contents and the remaining 20% is constituted by protein core. Gastric mucin M1 antigens are detected/found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in those of normal colon. Evidence from the literature suggestes that they are associated with the peptide core of mucins Resurgence of gastric mucin reactivity during colonic carcinogenesis is suggested to be due to either re-expression of the peptide core of gastric (or fetal colonic) mucins in the adult colon or due to changes in the glycosylation pattern of mucin which expose the hidden M1 antigens. |
| Immunogen | M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b-) patient |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | SPM297 |
| Host Species | Mouse |
| Tested Applications | IHC-P |
| For IHC-P: Ready to use for 30 min at RT. No special pretreatment is required. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanMouseMonkeyPigRatCatHedgehogRabbit |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | MUC5AC 4586 158373 MUC5 P98088 TBM leB |
|---|---|
| Target | Mucin 5AC |
| Cellular Localization | Cytoplasmic and cell surface |
| Light Chain Type | kappa |
Application
Human Stomach stained with anti-Mucin 5AC antibody
Application
Human Stomach Adenocarcinoma stained with anti-Mucin 5AC antibody
Application
Human Colon Adenocarcinoma stained with anti-Mucin 5AC antibody| Positive Control | Stomach |
|---|---|
| Application Notes | For IHC-P: Ready to use for 30 min at RT. No special pretreatment is required. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution and store at 4°C. Do not freeze. |
| Storage Buffer | Contains sodium azide |
