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MyD88 antibody

Catalog Number:OM264363
OM264363
Discount Price
OM264363-100ul
1~2 Week
100ul
OM264363-50ul
50ul
1~2 Week
Product Profile
Product Name MyD88 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [AT22F11] to MYD88This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Immunogen Recombinant human MYD88 (1-309aa) purified from E. coli
Key Feature
Clonality Monoclonal
Isotype IgG2
Clone Number AT22F11
Host Species Mouse
Tested Applications ELISAWB
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.:
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms MYD88D
myeloid differentiation primary response 88
Target MYD88
Light Chain Type kappa
Application

Application

WB analysis of Raji lysate (40ug) using MYD88 antibody at a dilution of 1:1,000.
Application Notes The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.:
Additional Information
Form Liquid
Storage Instructions Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Storage Buffer Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
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