Rabbit Polyclonal antibody to MYH8Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Myosin 8. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseDogRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MyHC pn MyHC peri gtMHC F myosin heavy chain 8 skeletal muscle perinatal
Target
MYH8
Tissue Specificity
Recognizes endogenous levels of Myosin 8 protein.
Application
Application
Western blot analysis of Myosin 8 expression in HeLa (A); SP2/0 (B); PC12 (C) whole cell lysates.
Application Notes
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.