Rabbit Polyclonal antibody to MYO5A (myosin VA (heavy chain 12, myoxin))This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human MYO5A. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, ChickenMouse (99%), Rat (97%), Chicken (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GS1 MYO5 MYH12 myosin VA (heavy chain 12 myoxin) MYR12
Target
MYO5A
Molecular Weight(MW)
215 kDa (note) (2)
Application
Application
Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with MYO5A antibody diluted at 1:500.
Positive Control
U87-MG , SK-N-SH
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.