Application
Western blot of myosin VIIa in mouse testes tissue extract using| Product Name | Myosin VIIa antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Myosin VIIaMyosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions. |
| Immunogen | Synthetic peptide: S(16)GQEFDVPIGAVVKLC(31).Immunizing peptide corresponds to amino acid residues 16-31 from mouse myosin VIIa. This sequence is completely conserved in mouse, porcine, and human myosin VIIa. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIPWB |
| ICC/IF: 1:50: |
|
| Species Reactivity | HumanMouseRatGuinea PigBovine |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | DFNA11 DFNB2 MYOVIIA MYU7A NSRD2 USH1B |
|---|---|
| Target | Myosin VIIa |
| Tissue Specificity | Detects Myosin VIIa from mouse tissues as well as recombinant. |
Application
Western blot of myosin VIIa in mouse testes tissue extract using| Application Notes | ICC/IF: 1:50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, 1 mg/ml BSA, 0.05% sodium azide |
