Application
Western blot analysis of NALP10 in human brain tissue lysate with NALP10 antibody at 1 ug/ml.Application
Immunofluorescence of NALP10 in human brain tissue with NALP10 antibody at 20 μg/mL.Application
Immunohistochemistry of NALP10 in human brain tissue with NALP10 antibody at 10 μg/mL.| Product Name | NALP10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to NALP10NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | LRR and PYD domainscontaining protein10 NOD8 NALP10 NLRP10 LRR and PYD domains-containing protein 10 NACHT PAN5 PYNOD LRR and PYD domainscontaining protein 10 CLR11.1 |
|---|---|
| Target | NALP10 |
| Tissue Specificity | This antibody is specific for NALP10 |
Application
Western blot analysis of NALP10 in human brain tissue lysate with NALP10 antibody at 1 ug/ml.
Application
Immunofluorescence of NALP10 in human brain tissue with NALP10 antibody at 20 μg/mL.
Application
Immunohistochemistry of NALP10 in human brain tissue with NALP10 antibody at 10 μg/mL.| Positive Control | Blocking Peptide: |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
