Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit polyclonal antibody to NALP8NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CLR19.2 LRR and PYD domainscontaining protein 8 NLRP8 NACHT LRR and PYD domainscontaining protein8 NALP8 LRR and PYD domains-containing protein 8 NOD16 PAN4
Target
NALP8
Tissue Specificity
This antibody is specific for NALP8
Application
Application
Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.