| Product Name | Nav 1.5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [4G8] to Nav 1.5Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signalling in nerves and muscles. Expression is also detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core alpha-subunit, together with one or more additional regulatoy beta-subunit. Expression has been detected in a number of tumour cell lines and has been implicated in the metastatic behaviour of breast and prostate cancer cells. |
| Immunogen | Peptide from an extracellular domain of Nav1.5 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 4G8 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| For ICC: Use at a concentration of 10μg/ml. For WB: Use at 2μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Voltage-gated Socium Channel Nav 1.5 CDCD2 antibody CMD1E antibody CMPD2 antibody HB1 antibody HB2 antibody HH1 antibody IVF antibody LQT3 antibody Scn5a (gene name) antibody Sodium channel protein cardiac muscle alpha-subunit antibody Sodium channel prot |
|---|---|
| Target | Nav 1.5 |
| Positive Control | HEK293 recombinant cell line over expressing Nav 1.5 |
|---|---|
| Application Notes | For ICC: Use at a concentration of 10μg/ml. For WB: Use at 2μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2 |
