Mouse monoclonal antibody [S68-6] to NAV1.7This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq]
Immunogen
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7, accession number Q15858
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
S68-6
Host Species
Mouse
Tested Applications
ICC/IFIHCIPWB
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Gene Synonyms
voltage gated sodium channel subunit alpha Nav1 SCN9A ETHA NE NA hNE Na neuroendocrine sodium channel peripheral sodium channel1 PN1 peripheral sodium channel 1
Target
NAV1.7
Molecular Weight(MW)
230kDa (note)
Tissue Specificity
No cross-reactivity against other Nav channels.
Cellular Localization
In neurite terminals.
Application
Application
Western blot analysis of Nav1.7 in CHO cells using a 1:1000 dilution of
Application
IHC analysis of Nav1.7 in mouse brain tissue using a dilution of
Application Notes
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).:
Additional Information
Form
Liquid
Storage Instructions
Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.