| Product Name | Nestin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [2C1.3A11] to NestinNestin is a Class VI intermediate filament expressed in the developing central nervous system (CNS) in early embryonic neuroepithelial stem cells. This protein has been widely used as a predominant marker for stem / progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS. Furthermore, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumor. This highly specific antibody to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. |
| Immunogen | The immunogen corresponding to a region within amino acids 1464 and 1614 of human Nestin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2C1.3A11 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIHCIPWB |
| For WB: Use at 1:1000-1:5000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | FLJ21841 10763 Nbla00170 P48681 NES Nestin 600915 |
|---|---|
| Target | Nestin |
| Molecular Weight(MW) | 177KDa (note) |
| Tissue Specificity | Human nestin with no cross- reactivity to rodent |
| Application Notes | For WB: Use at 1:1000-1:5000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 2-8°C. For extended storage, aliquot and store at -20°C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | PBS + 0.1% sodium azide |
