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Neuritin antibody

Catalog Number:OM265034
OM265034
Discount Price
OM265034-100ul
1~2 Week
100ul
OM265034-50ul
50ul
OM265034-20ul
20ul
1~2 Week
Product Profile
Product Name Neuritin antibody
Antibody Type Primary Antibodies
Product description Rabbit polyclonal antibody to NeuritinAs the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAIHC-PWB
For WB: Use at a concentration of 5-10 μg/mL.:
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms Neuritin
NRN1
cpg15
Target Neuritin
Tissue Specificity This antibody is specific for Neuritin
Application

Application

Immunohistochemistry of Neuritin in mouse heart tissue with Neuritin antibody at 5 ug/ml.

Application

Western blot analysis of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 ug/ml.

Application

Immunohistochemistry of Neuritin in human brain tissue with Neuritin antibody at 2.5 μg/ml.

Application

Immunofluorescence of Neuritin in Mouse Heart cells with Neuritin antibody at 20 ug/mL.
Positive Control Daudi Cell Lysate, Mouse Heart Tissue, Human Brain Tissue
Application Notes For WB: Use at a concentration of 5-10 μg/mL.:
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer PBS containing 0.02% sodium azide
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