| Product Name | NGF antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [AS21] to NGFNerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture NGF induces the formation of neurite projections and in vivo may stimulate the innervation of tissues. NGF plays a role in the repair, regeneration, and protection of neurons, and as such could serve as a therapeutic agent in neurodegenerative conditions such as Alzheimer's disease. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | AS21 |
| Host Species | Mouse |
| Tested Applications | ELISANeutWB |
| ELISA: Use at a concentration of 10 μg/ml for coating in a two site ELISA with biotin conjugated NGF antibody (GTX16160) for mouse NGF. Neut: This antibody has been used to neutralize > 90% human NGF bioactivity on PC12 cells at a 200 fold molar excess. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | Beta-NGF HSAN5 MGC161426 MGC161428 NGFB Beta NGF BetaNGF |
|---|---|
| Target | NGF |
| Tissue Specificity | Recognises 2.5S, 7S and bNGF. |
| Cellular Localization | Secreted |
| Application Notes | ELISA: Use at a concentration of 10 μg/ml for coating in a two site ELISA with biotin conjugated NGF antibody (GTX16160) for mouse NGF. Neut: This antibody has been used to neutralize > 90% human NGF bioactivity on PC12 cells at a 200 fold molar excess. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.08% Sodium Azide; Constituents: PBS |
