| Product Name | NKX2.1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [pool] to NKX2.1This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Apr 2011] |
| Immunogen | Full length protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | pool |
| Host Species | Mouse |
| Tested Applications | WB |
| WB: Use at a dilution of 1/500 - 1/1000. Detects a band of approximately 42 kDa (predicted molecular weight: 44.5 kDa). For optimal results, primary antibody incubations should be performed at 4°C. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BCH NK-2 NKX2-1 TTF-1 TEBP TITF1 BHC NKX2A TTF1 |
|---|---|
| Target | NKX2.1 |
| Tissue Specificity | reacts with human TTF1. |
| Cellular Localization | Nuclear |
| Positive Control | NCI-H661 nuclear extract |
|---|---|
| Application Notes | WB: Use at a dilution of 1/500 - 1/1000. Detects a band of approximately 42 kDa (predicted molecular weight: 44.5 kDa). For optimal results, primary antibody incubations should be performed at 4°C. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide, 0.01% thimerosal Constituents: 0.2% Gelatin, PBS |
