| Product Name | NMDA receptor 3A + 3B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal to NMDAR3A + 3BTwo new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate. |
| Immunogen | Fusion protein, corresponding to amino acids 780-914 from the intracellular IIIIV loop of Human NR3A + NR3B. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB: Use at a concentration of 1 - 10 μg/ml. Predicted molecular weight: 120-133 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | FLJ45414 NR3B NMDAR-L NR3A NMDAR L NMDARL |
|---|---|
| Target | NMDA receptor 3A + 3B |
| Tissue Specificity | This antibody recognizes NMDAR subunits NR3A and NR3B. It does not cross react with subunits NR1 or NR2AD. |
| Application Notes | WB: Use at a concentration of 1 - 10 μg/ml. Predicted molecular weight: 120-133 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least one (1) year at -20 °C to -70 °C. Aliquot before frezing to avoid repeated freeze / thaw cycles. |
| Storage Buffer | Preservative: NoneConstituents: PBS. pH 7.4 |
