Application
Western blot of Noxa in A) human, B) mouse, and C) rat thymus tissue using antibody at 2 ug/ml.Application
Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PMAIP1 antibody at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Product Name | Noxa antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NoxaPromotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to TP53/p53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. |
| Immunogen | Synthetic peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB (1 - 2 µg/ml), IHC-P (10 µg/ml) | |
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Protein G |
| Gene Synonyms | Noxa, PMA INDUCED PROTEIN 1, PMAINDUCED PROTEIN 1 |
|---|---|
| Target | Noxa |
| Tissue Specificity | A mixture of synthetic peptides containing amino acids 51-66 and 75-90 of mouse Noxa. |
Application
Western blot of Noxa in A) human, B) mouse, and C) rat thymus tissue using antibody at 2 ug/ml.
Application
Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PMAIP1 antibody at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Application Notes | WB (1 - 2 µg/ml), IHC-P (10 µg/ml) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Long term: -20°C; Short term: +4°C |
| Storage Buffer | PBS, 0.05% BSA, 0.05% sodium azide. |
