Application
Human Pancreas (formalin-fixed, paraffin-embedded) stained with PMAIP1 antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Product Name | Noxa antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NoxaPromotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to TP53/p53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. |
| Immunogen | Synthetic peptide |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB (0.5 - 1 µg/ml), IHC-P (5 µg/ml) | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Noxa, PMA INDUCED PROTEIN 1, PMAINDUCED PROTEIN 1 |
|---|---|
| Target | Noxa |
| Tissue Specificity | synthetic peptide corresponding to 17 amino acids at the amino terminus of mouse Noxa |
Application
Human Pancreas (formalin-fixed, paraffin-embedded) stained with PMAIP1 antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Application Notes | WB (0.5 - 1 µg/ml), IHC-P (5 µg/ml) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C, avoid repeated freeze thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide. |
