Application
WB analysis of extracts from various cells using NR0B2 antibody.Application
IHC-P analysis of rat lung using NR0B2 antibody at a dilution of 1:100.Application
IHC-P analysis of rat brain using NR0B2 antibody at a dilution of 1:100.Application
IHC-P analysis of mouse brain using NR0B2 antibody at a dilution of 1:100.Application
ICC/IF analysis of U2OS cells using NR0B2 antibody (green) and DAPI (blue).| Product Name | NR0B2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NR0B2The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human NR0B2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | nuclear receptor subfamily 0 group B member 2 SHP SHP1 |
|---|---|
| Target | NR0B2 |
| Molecular Weight(MW) | 28 kDa (note) |
Application
WB analysis of extracts from various cells using NR0B2 antibody.
Application
IHC-P analysis of rat lung using NR0B2 antibody at a dilution of 1:100.
Application
IHC-P analysis of rat brain using NR0B2 antibody at a dilution of 1:100.
Application
IHC-P analysis of mouse brain using NR0B2 antibody at a dilution of 1:100.
Application
ICC/IF analysis of U2OS cells using NR0B2 antibody (green) and DAPI (blue).| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
