Application
Western blot analysis of extracts of various cell lines, using NR1I3 antibody.Application
Immunohistochemistry of paraffin-embedded rat lung using NR1I3 antibody at dilution of 1:100 (x400 lens).Application
Immunofluorescence analysis of U2OS cell using NR1I3 antibody. Blue: DAPI for nuclear staining.| Product Name | NR1I3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NR1I3This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant protein of human NR1I3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MB67 nuclear receptor subfamily 1 group I member 3 CAR1 CAR |
|---|---|
| Target | NR1I3 |
Application
Western blot analysis of extracts of various cell lines, using NR1I3 antibody.
Application
Immunohistochemistry of paraffin-embedded rat lung using NR1I3 antibody at dilution of 1:100 (x400 lens).
Application
Immunofluorescence analysis of U2OS cell using NR1I3 antibody. Blue: DAPI for nuclear staining.| Application Notes | WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
