Application
Immunohistochemical staining of human tissue sections using NR4A3 antibody| Product Name | NR4A3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Nuclear Receptor NOR-1 (NR4A3)NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by a variety of stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats. Three human protein isoforms have been documented: NOR-1, NOR-1beta, and NOR-1 3' variant. NOR-1 expression has been documented in human brain, heart, placenta, kidney, skeletal muscle, fetal brain and fetal lung. ESTs have been isolated from human tissue libraries, including cancerous head/neck and skin, and normal prostate, skin, liver, testis, skeletal muscle, blood and B-cell/lung/testis. Caution: The symbol NOR-1 is also used to describe a nitric oxide-donor reagent. Tec is also the name of a kinase on chromosome 4. |
| Immunogen | Synthetic peptide - KLH conjugated. Peptide sequence identity/similarity to Mouse: 65/75%, Rat: 65/75%. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | AI573420 CHN CSMF MINOR NOR-1 Nor1 TEC NOR 1 |
|---|---|
| Target | NR4A3 |
Application
Immunohistochemical staining of human tissue sections using NR4A3 antibody| Application Notes | For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.01% sodium azide |
