Application
Human Skin (formalin-fixed, paraffin-embedded) stained with NPM1 antibody at 1:50 followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Product Name | Nucleophosmin (phospho Thr234/Thr237) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to NPM1 (phospho Thr234/Thr237)NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM] |
| Immunogen | Synthetic peptide |
| Modification | p-Thr234/Thr237 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB, IHC-P (1:50): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | B23 MGC104254 NPM NPM1 (phospho T234/T237) NPM1 (phospho Thr234/Thr237) NPM1 (pT234/pT237) NPM1 (pThr234/pThr237) NPM1 phospho T234/T237 NPM1 phospho Thr234/Thr237 Phospho NPM1 (T234/T237) Phospho NPM1 (Thr234/Thr237) Phospho NPM1 (pT234/pT237) |
|---|---|
| Target | NPM1 |
| Tissue Specificity | Modified peptide |
Application
Human Skin (formalin-fixed, paraffin-embedded) stained with NPM1 antibody at 1:50 followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.| Application Notes | WB, IHC-P (1:50): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol. BSA is present at 1 mg/ml final concentration (USA origin). |
