Rabbit polyclonal antibody to Oct-1Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHCWB
Western blotting (0.5-4 µg/ml). Based on researchers feed back, it also works in Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually.:
Western blot analysis of Oct-1 in Jurkat cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). Based on researchers feed back, it also works in Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.