Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with OLR1 Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Western blot analysis of OLR1 Antibody (Center) in HL-60 cell line lysates (35ug/lane).OLR1 (arrow) was detected using the purified Pab.Application
Western blot analysis of OLR1 (arrow) using rabbit polyclonal OLR1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2) .| Product Name | OLR1 / LOX-1 antibody, Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to OLR1 / LOX-1This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
| Immunogen | KLH conjugated synthetic peptide between 71~100 amino acids from the Center region of human OLR1 / LOX-1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| ELISA: Use at 1:1,000: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | OLR1 Ctype lectin domain family 8 member A LOX-1 Lectintype oxidized LDL recepto Lectinlike oxidized LDL receptor1 Lectinlike oxLDL receptor1 Lectin-type oxidized LDL receptor 1 Oxidized lowdensity lipoprotein receptor 1 OxLDL receptor 1 Lectintyp |
|---|---|
| Target | OLR1 / LOX-1 |
| Molecular Weight(MW) | 30.959 kDa (note) |
| Cellular Localization | A secreted form also exists. |
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with OLR1 Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Western blot analysis of OLR1 Antibody (Center) in HL-60 cell line lysates (35ug/lane).OLR1 (arrow) was detected using the purified Pab.
Application
Western blot analysis of OLR1 (arrow) using rabbit polyclonal OLR1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OLR1 gene (Lane 2) .| Application Notes | ELISA: Use at 1:1,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
