| Product Name | OSCAR antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [6S6] to OSCAROsteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant OSCAR EC domain |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 6S6 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB(1:500-1000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | osteoclast associated immunoglobulin-like receptor PIGR3 |
|---|---|
| Target | OSCAR |
| Tissue Specificity | This antibody was selected for its ability to detect human OSCAR. |
| Application Notes | WB(1:500-1000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
