Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with OTOF antibody at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.
Rabbit polyclonal antibody to OTOFMutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has 3 C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has 6 C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Synthetic peptide - KLH conjugated
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC-P
ELISA (1:0 - 1:1000), IHC-P (20 µg/ml):
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Protein G
Target Information
Gene Synonyms
AUNB1 DFNB6 DFNB9 FER1L2 NSRD9
Application
Application
Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with OTOF antibody at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody LS-D1, alkaline phosphatase-streptavidin and chromogen.