| Product Name | p19 INK4d antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [IMD-19] to p19 INK4dThe protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal prolife251ion, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | IMD-19 |
| Host Species | Mouse |
| Tested Applications | IHC-PWB |
| IHC-P:1:10~1:50 WB:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | p19 CDKN2D cyclin-dependent kinase inhibitor 2D (p19 inhibits CDK4) p19-INK4D INK4D |
|---|---|
| Target | P19 |
| Tissue Specificity | Human. No cross reactivity with other proteins. |
| Application Notes | IHC-P:1:10~1:50 WB:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1.2% sodium acetate or neutral PBS. |
