Application
FACS analysis of human peripheral blood granulocytes using p22phox antibody [CS9].| Product Name | p22phox antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [CS9] to p22phoxCytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008] |
| Immunogen | p22phox solubilised in octyl-beta-gluycopyranoside |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | CS9 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIHC-FIPWB |
| Flow Cytometry: 1/10 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CYBA cytochrome b-245 alpha polypeptide p22-PHOX |
|---|---|
| Target | p22phox |
| Tissue Specificity | This antibody recognizes the light chain of cytochrome B245, also known as p22phox. Clone CS9 also has an inhibitory effect on NADPH oxidase activation. |
Application
FACS analysis of human peripheral blood granulocytes using p22phox antibody [CS9].| Application Notes | Flow Cytometry: 1/10 - 1/100 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) |
