Application
Application| Product Name | p53R2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to p53R2The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2 (1), Chk2 (2), p53AIP1 (3), Noxa (4), PIDD (5), and PID/MTA2 (6), were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase (1,7). P53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73also induces p53R2 expression (8). p53R2 is an important target of p53 for tumor suppression. |
| Immunogen | Synthetic peptide: GDPERPEAAGLDQDER, corresponding to amino acids 2-17 of Human p53R2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| This antibody can be used for detection of p53R2 byWestern blot at 0.5 to 1 μg/ml and a 39 kDa band can bedetected.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Gene Synonyms | DKFZp686M05248 MGC102856 MGC42116 MTDPS8A MTDPS8B P53R2 |
|---|---|
| Target | p53R2 |
Application
Application| Positive Control | A431 or 3T3 cell lysate |
|---|---|
| Application Notes | This antibody can be used for detection of p53R2 byWestern blot at 0.5 to 1 μg/ml and a 39 kDa band can bedetected.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. |
| Storage Buffer | PBS with 0.02% sodium azide |
