Mouse monoclonal antibody [3E3] to p57 Kip2This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Immunogen
The immunogen corresponding to human CDKN1C expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3E3
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CDKN1C P57 P57KIP2 WBS KIP2 BWCR BWS
Target
p57 Kip2
Molecular Weight(MW)
57 kDa (note)
Application
Application
Western blot analysis using CDKN1C mAb against HEK293 (1) and CDKN1C (AA: 214-316)-hIgGFc transfected HEK293 (2) cell lysate.
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.