Application
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng)Application
Western blot analysis using p63α mouse mAb against A431 (1), Hela (2), Jurkat (3), THP-1 (4), NIH/3T3 (5), Cos7 (6) and PC-12 (7) cell lysate.Application
Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and lung cancer (right) using p63α mouse mAb with DAB staining.| Product Name | p63 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4E5] to p63This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-l |
| Immunogen | The immunogen corresponding to human p63a. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4E5 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | HumanMouseMonkeyRat |
| Concentration | 1mg/ml |
| Gene Synonyms | P53CP P51 AIS TP63 P73H P40 TP53CP B(P51A) LMS NBP EEC3 OFC8 SHFM4 KET TP73L B(P51B) Antib |
|---|---|
| Target | p63 |
| Molecular Weight(MW) | 51 kDa (note) |
Application
Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng)
Application
Western blot analysis using p63α mouse mAb against A431 (1), Hela (2), Jurkat (3), THP-1 (4), NIH/3T3 (5), Cos7 (6) and PC-12 (7) cell lysate.
Application
Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and lung cancer (right) using p63α mouse mAb with DAB staining.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
