Rabbit Polyclonal antibody to PAF1 (Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae))PAF1, parafibromin (CDC73; MIM 607393), LEO1 (MIM 610507), and CTR9 (MIM 609366) form the PAF protein complex that associates with the RNA polymerase II subunit POLR2A (MIM 180660) and with a histone methyltransferase complex (Rozenblatt-Rosen et al., 2005 [PubMed 15632063]). The PAF complex also has a role in histone monoubiquitination (Zhu et al., 2005 [PubMed 16307923]).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the center region of human PAF1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Mouse
Predicted Reactivity
Human, Rat, Zebrafish, Xenopus laevis, Chimpanzee, BovineHuman (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (93%), Chimpanzee (100%), Bovine (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
F23149_1 antibody FLJ11123 antibody PD2 antibody PAF1 antibody pancreatic differentiation protein 2 antibody hPAF1 antibody RNA polymerase II-associated factor 1 homolog antibody Paf1 RNA polymerase II associated factor homolog (S. cerevisiae) ant
Molecular Weight(MW)
60 kDa (note) (3)
Cellular Localization
Nucleus
Application
Application
Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE diluted at 1:1000
Positive Control
mouse brain
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.