Application
Human PAK1 detected by Western blot in transfected HEK293 cells (left lane)| Product Name | PAK1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PAK1Human p21-GTPase-activated Protein Kinase 1 (PAK 1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK 1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK 1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK 1 induces neurite outgrowth. PAK 1 may also regulate NF kappa B activation. |
| Immunogen | Recombinant protein - human PAK 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| For WB: Use at a dilution of 1:4,500 - 1:5,500. The use of this product can also be used for IP but not yet reported. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MGC130000 MGC130001 PAKalpha |
|---|---|
| Target | PAK1 |
Application
Human PAK1 detected by Western blot in transfected HEK293 cells (left lane)| Application Notes | For WB: Use at a dilution of 1:4,500 - 1:5,500. The use of this product can also be used for IP but not yet reported. Optimal dilutions/concentrations should be determined by the researcher.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide |
