Application
ELISA analysis of control antigen and antigen using PAX5 antibody [7D3].Application
WB analysis of (1) Raji and (2) EVC-304 lysates using PAX5 antibody [7D3].Application
WB analysis of human PAX5 recombinant protein using PAX5 antibody [7D3].| Product Name | PAX5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal Antibody [7D3] to PAX5This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of trans |
| Immunogen | The immunogen corresponding to a region within amino acids 235 and 382 of human PAX5 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7D3 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | BSAP |
|---|---|
| Target | PAX5 |
| Molecular Weight(MW) | 45 kDa (note) |
Application
ELISA analysis of control antigen and antigen using PAX5 antibody [7D3].
Application
WB analysis of (1) Raji and (2) EVC-304 lysates using PAX5 antibody [7D3].
Application
WB analysis of human PAX5 recombinant protein using PAX5 antibody [7D3].| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 4°C; -20°C for long term storage |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
