Rabbit polyclonal antibody to PC2This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western Blotting: 1/500 - 1/1000 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
HumanMonkeyRat
Concentration
1mg/ml
Purification
Serum
Target Information
Gene Synonyms
PCSK2 SPC2 NEC-2 NEC2 PC2 NEC 2
Target
NEC2
Tissue Specificity
This antibody recognizes the peptidase enzyme designated proprotein convertase 2 and also known as PC2, NEC2 and neuroendocrine convertase 2.
Application Notes
Western Blotting: 1/500 - 1/1000 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.