Application
Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 ug/ml.Application
Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 2 ug/ml.| Product Name | PCDH12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PCDH12Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | vascular endothelial cadherin2 PCDH12 VE-cadherin 2 Protocadherin12 vascular endothelial cadherin 2 Protocadherin 12 VEcadherin 2 VECAD2 VEcadherin2 VE cadherin 2 |
|---|---|
| Target | PCDH12 |
| Tissue Specificity | This antibody is specific for PCDH12 |
Application
Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 ug/ml.
Application
Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85342-PEP - PCDH12 Peptide Lysates: Cat. No. GTX27911 - K562 Cell Lysate |
|---|---|
| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
