Rabbit Polyclonal antibody to PD1This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
Immunogen
PD-1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P: 5 ug/mL:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Western blot analysis of PD-1 in THP-1 cell lysate with PD-1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.
Application
Immunohistochemistry of PD-1 in human brain tissue with PD-1 antibody at 5 ug/mL.
Application Notes
IHC-P: 5 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.