Rabbit polyclonal to PDE9APDE9A catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. PDE9A is widely expressed in various tissues, including spleen, small intestine and brian.
Immunogen
Synthetic cyclic peptide (Human) (C terminal).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIPWB
IHC: Use at an assay dependent dilution. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/500. Detects a band of approximately 70-73 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ90181 HSPDE9A2
Target
PDE9A
Tissue Specificity
This antibody does not cross-react with PDE9B protein or any other PDE family members.
Application
Application
Western blot of PDE9A using PDE9A-selective antibody
Application Notes
IHC: Use at an assay dependent dilution. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/500. Detects a band of approximately 70-73 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Storage Buffer
Stabilization buffer' with 0.02% thimerosal or merthiolate.