| Product Name | PDGF Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [35248 (57/20)] to PDGF Receptor alphaThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012] |
| Immunogen | Purified recombinant human PDGF Receptor beta (extracellular domain) derived from the insect cell line Sf21. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 35248 (57/20) |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-PWB |
| ELISA: 0.5 µg/ml - 1 µg/ml: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDGFR2 RHEPDGFRA PDGFR-2 PDGFRA CD140A |
|---|---|
| Target | CD140A |
| Tissue Specificity | This antibody recognizes the human PDGF Receptor alpha. Clone 35248 has been reported for use in functional studies. |
| Application Notes | ELISA: 0.5 µg/ml - 1 µg/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) 1.5% Trehalose |
