Mouse monoclonal antibody [1A2] to PDGF Receptor betaThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human PDGFRβ expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A2
Host Species
Mouse
Tested Applications
ELISAWB
ELISA: 1/10000.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Target Information
Gene Synonyms
PDGFR1 CD140B JTK12 PDGFR-1 PDGFRB IBGC4
Target
PDGFRβ
Molecular Weight(MW)
190 kDa (note)
Application
Application
Western blot analysis using anti-PDGFR
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.