| Product Name | PDGF Receptor beta antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [5C37] to PDGF Receptor betaThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant hPGFDR beta N-terminal |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 5C37 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Western Blot(1:400-1000)|Immunohistochemistry(1:50 -500): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDGFRB IBGC4 CD140B PDGFR JTK12 PDGFR1 platelet-derived growth factor receptor beta polypeptide PDGFR-1 |
|---|---|
| Target | PDGF receptor beta |
| Tissue Specificity | This antibody detects human PDGF Receptor beta in western blots |
| Application Notes | Western Blot(1:400-1000)|Immunohistochemistry(1:50 -500): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
