Application
WB analysis of extracts from various cells using PDGF-B antibody.Application
IHC-P analysis of human stomach cancer using PDGF-B antibody at a dilution of 1:200.Application
IHC-P analysis of rat spleen tissue using PDGF-B antibody at a dilution of 1:200.| Product Name | PDGF-B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PDGF-BThe protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013] |
| Immunogen | Recombinant protein of human PDGFB |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDGFB SIS c-sis SSV platelet-derived growth factor beta polypeptide PDGF2 PDGF-2 |
|---|---|
| Target | PDGF-B |
| Molecular Weight(MW) | 27 kDa (note) |
Application
WB analysis of extracts from various cells using PDGF-B antibody.
Application
IHC-P analysis of human stomach cancer using PDGF-B antibody at a dilution of 1:200.
Application
IHC-P analysis of rat spleen tissue using PDGF-B antibody at a dilution of 1:200.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
